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Berberine HCL, Berberine Hydrocloride, Berberine Chloride

Short Description:

  • Synonyms: Berberine Hydrocloride, Berberine Chloride
  • Appearance: Yellow Fine Powder, Bitter
  • Active ingredients:Berberine HCL (Berberine Hydrocloride)

Product Detail

Product Tags

Specification

97%-98% Berberine HCL (Berberine Hydrocloride) as per CP2015

Introduction

Berberine HCL (Berberine Hydrocloride CAS NO. 141433-60-5, Molecular: C20H18ClNO4) is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids.

Berberine HCL (Berberine Hydrocloride CAS NO. 141433-60-5, Molecular: C20H18ClNO4) is a yellow crystal powder, no odour, extremely bitter, it can be soluble in hot water, and slightly soluble in water or ethanol. According to the solvent used in production, it can be reacted into Berberine hydrochloride and Berberine sulfate

Application

The bark is categorized in a traditional Chinese medicine counterpart of humorism, affecting the kidney, urinary bladder and large intestine meridians.

Berberine HCL (Berberine Hydrocloride CAS NO. 141433-60-5, Molecular: C20H18ClNO4) has A natural broad-spectrum antibiotic inhabits pathogenic microorganisms, such as bacteria, fungi, and protozoa, for the treatment of many diseases.

Berberine HCL (Berberine Hydrocloride CAS NO. 141433-60-5, Molecular: C20H18ClNO4) has antibacterial action on Gram-positive bacteria and Gram-negative bacteria, such as E. coli, pneumococcal, staphylococcus aureus, streptococcus, and salmonella typhi. Especially a strong antibacterial action on shigella dysenteriae, it also has some inhibitory effects on influenza virus, amoeba, leptospira and certain dermatophytes.

Berberine sulfate is usually used in veterinary product and pesticide industry, it has good water solubility.

Certificate of Analysis For Reference

Product Name: Berberine HCL Botanical Name:
Batch Number: 20201108 Used Part:
Batch Quantity: 500KG Analysis Date: Nov. 8, 2020
Manufacture Date: Nov. 8, 2020 Certificate Date: Nov.12, 2020

ITEM

SPECIFICATION

RESULTS

Description:
Appearance
Odor
Taste
Particle size
Extract Solvent
Light Yellow crystalline Powder
Odorless
Extreme Bitter
100% pass 80 mesh sieve
Water & hydrochloric acid
Conforms
Conforms
Conforms
Conforms
Assay:
Berberine HCL
≥97% by Titration (CP2015) 98.02%
Physical:
Loss on Drying
Residue on ignition
 ≤12.0 %
≤0.2 %
10.80%
0.18%
Chemical:
Heavy Metals
Arsenic (As)
Lead (Pb)
Mercury (Hg)
Cadmium (Cd)
Solvent Residue
Methanol
Ethanol
 ≤10 ppm
≤2ppm
≤5ppm
≤0.1ppm
≤1ppm
≤100ppm
≤500ppm
Conforms
0.184ppm
0.022ppm
0.006ppm
0.012ppm
2.18ppm
1.46ppm
Microbial:
Total Plate Count
Yeast & Mold
E. Coli
Salmonella spp
Staphylococcus aureus
Pseudomonas aeruginosa
≤1000cfu/g
≤100cfu/g
Absent
Absent
Absent
Absent
Conforms
Conforms
Conforms
Conforms
Conforms
Conforms

Conclusion Conform to specification CP2015
Storage Store in cool & dry place. Keep away from strong light and heat.
Shelf life 24 months when properly stored.


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