Berberine HCL, Berberine Hydrocloride, Berberine Chloride
Specification
97%-98% Berberine HCL (Berberine Hydrocloride) as per CP2015
Introduction
Berberine HCL (Berberine Hydrocloride CAS NO. 141433-60-5, Molecular: C20H18ClNO4) is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids.
Berberine HCL (Berberine Hydrocloride CAS NO. 141433-60-5, Molecular: C20H18ClNO4) is a yellow crystal powder, no odour, extremely bitter, it can be soluble in hot water, and slightly soluble in water or ethanol. According to the solvent used in production, it can be reacted into Berberine hydrochloride and Berberine sulfate
Application
The bark is categorized in a traditional Chinese medicine counterpart of humorism, affecting the kidney, urinary bladder and large intestine meridians.
Berberine HCL (Berberine Hydrocloride CAS NO. 141433-60-5, Molecular: C20H18ClNO4) has A natural broad-spectrum antibiotic inhabits pathogenic microorganisms, such as bacteria, fungi, and protozoa, for the treatment of many diseases.
Berberine HCL (Berberine Hydrocloride CAS NO. 141433-60-5, Molecular: C20H18ClNO4) has antibacterial action on Gram-positive bacteria and Gram-negative bacteria, such as E. coli, pneumococcal, staphylococcus aureus, streptococcus, and salmonella typhi. Especially a strong antibacterial action on shigella dysenteriae, it also has some inhibitory effects on influenza virus, amoeba, leptospira and certain dermatophytes.
Berberine sulfate is usually used in veterinary product and pesticide industry, it has good water solubility.
Certificate of Analysis For Reference
| Product Name: | Berberine HCL | Botanical Name: | |
| Batch Number: | 20201108 | Used Part: | |
| Batch Quantity: | 500KG | Analysis Date: | Nov. 8, 2020 |
| Manufacture Date: | Nov. 8, 2020 | Certificate Date: | Nov.12, 2020 |
|
ITEM |
SPECIFICATION |
RESULTS |
| Description: Appearance Odor Taste Particle size Extract Solvent |
Light Yellow crystalline Powder Odorless Extreme Bitter 100% pass 80 mesh sieve Water & hydrochloric acid |
Conforms Conforms Conforms Conforms |
| Assay: Berberine HCL |
≥97% by Titration (CP2015) | 98.02% |
| Physical: Loss on Drying Residue on ignition |
≤12.0 % ≤0.2 % |
10.80% 0.18% |
| Chemical: Heavy Metals Arsenic (As) Lead (Pb) Mercury (Hg) Cadmium (Cd) Solvent Residue Methanol Ethanol |
≤10 ppm ≤2ppm ≤5ppm ≤0.1ppm ≤1ppm ≤100ppm ≤500ppm |
Conforms 0.184ppm 0.022ppm 0.006ppm 0.012ppm 2.18ppm 1.46ppm |
| Microbial: Total Plate Count Yeast & Mold E. Coli Salmonella spp Staphylococcus aureus Pseudomonas aeruginosa |
≤1000cfu/g ≤100cfu/g Absent Absent Absent Absent |
Conforms Conforms Conforms Conforms Conforms Conforms |
Conclusion Conform to specification CP2015
Storage Store in cool & dry place. Keep away from strong light and heat.
Shelf life 24 months when properly stored.
