Cnidium Fruit Extract, Osthole
Specification
10%-25% Osthole By HPLC from Liquid to Paste
10%, 30%, 80%, 90%, 98% Osthole by HPLC Powder from Brown to White Color
Introduction
The main bioactivator compounds in Fructus Cnidii Extract are coumarins,which includes osthole, bergapten, isopimpinellin, columbianadin, archangelicin, edultin, O-acetylcolumianetin, O-isovalerycolumbianetin, cniforin A, xanthotoxol, xanthotoxin, imperatorin etc.
Osthole (CAS NO. 484-12-8, Molecular Formula: C15H16O3) also called as Osthol, is a kind of coumarins in the Fructus Cnidii Extract, which is extracted from the seed (Fructus Cnidii)of the plant “Cnidium monnieri (L.) Cuss.”.
Osthole has functions of Antifungus, Antivirus, anti-inflammatory, anesthetization and Enhancing Immune etc.
Application
1) Pharmaceutical field to stimulate sexual desire and enhance human immunity.
2) Cosmetic Field to Improve the pathological changes of psoriasis, with strong anti-inflammatory, anti-allergy, antipruritic effect
3) Osthole: A natural ingredient in botanical Pesticides & Bactericide (botanical source) to control diseases and pests:
A) It has inhibitory effect on gibberellum and Rhizoctonia solani of wheat.
B) As for cucumber and cabbage downy mildew, cucumber powdery mildew, apple leaf blight, orthomycosis and other plant pathogens Fungi, The Osthole has a broad spectrum of inhibitory activity.
C) Killing effect on the larval lepidoptera tea geometrid, plutella xylostella, rapeseed, the newly hatched noctuidae, aphid.
Certificate Of Analysis For Reference
| Product Name: | Cnidium Fruit Extract | Botanical Name: | Cnidium monnieric(L.)Cuss | ||||
| Batch Number: | 20210510 | Used Part: | Fruit | ||||
| Batch Quantity: | 800KG | Analysis Date: | May 15, 2021 | ||||
| Manufacture Date: | May 10, 2021 | Certificate Date: | May 15, 2021 | ||||
| ITEM | SPECIFICATION | RESULTS | ||||
| Description: Appearance Odor&Taste Extract Solvent |
Dark Brown Oleamen Characteristics Methanol & Water |
Conforms Conforms Conforms |
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| Assay: Osthole |
≥10% by HPLC | 11.27% | ||||
| Physical: PH Specific Gravity |
6-8 | 7.20 1.03 |
||||
| Chemical: Heavy Metals Arsenic (As) Lead (Pb) Mercury (Hg) Cadmium (Cd) |
≤10 ppm ≤2ppm ≤5ppm ≤0.1ppm ≤1ppm |
Conforms Conforms Conforms Conforms Conforms |
||||
| Microbial: Total Plate Count Yeast & Mold E. Coli Salmonella spp Staphylococcus aureus Pseudomonas aeruginosa |
≤1000cfu/g ≤100cfu/g Absent Absent Absent Absent |
Conforms Conforms Conforms Conforms Conforms Conforms |
||||
Conclusion: Conform to specification.
Storage: Store in cool & dry place. Keep away from strong light and heat.
Shelf life: 24 months when properly stored.
| Product Name: | Cnidium Fruit Extract | Botanical Name: | Cnidium monnieric(L.)Cuss | ||||
| Batch Number: | 20210414 | Used Part: | Fruit | ||||
| Batch Quantity: | 55KG | Analysis Date: | April 19, 2020 | ||||
| Manufacture Date: | April 14, 2021 | Certificate Date: | April 19, 2020 | ||||
| ITEM | SPECIFICATION | RESULTS | ||||
| Description: Appearance Odor&Taste Extract Solvent |
Dark Brown Oleamen Characteristics Methanol & Water |
Conforms Conforms Conforms |
||||
| Assay: Osthole |
≥20% by HPLC | 22.86% | ||||
| Physical: PH Specific Gravity |
6-8 ≥1.10 |
7.00 1.22 |
||||
| Chemical: Heavy Metals Arsenic (As) Lead (Pb) Mercury (Hg) Cadmium (Cd) |
≤10 ppm ≤2ppm ≤5ppm ≤0.1ppm ≤1ppm |
Conforms Conforms Conforms Conforms Conforms |
||||
| Microbial: Total Plate Count Yeast & Mold E. Coli Salmonella spp Staphylococcus aureus Pseudomonas aeruginosa |
≤1000cfu/g ≤100cfu/g Absent Absent Absent Absent |
Conforms Conforms Conforms Conforms Conforms Conforms |
||||
Conclusion: Conform to specification.
Storage: Store in cool & dry place. Keep away from strong light and heat.
Shelf life: 24 months when properly stored.
| Product Name: | Cnidium Fruit Extract | Botanical Name: | Cnidium monnieric(L.)Cuss | ||||
| Batch Number: | 20210325 | Used Part: | Fruit | ||||
| Batch Quantity: | 150KG | Analysis Date: | April 2, 2021 | ||||
| Manufacture Date: | March 25, 2021 | Certificate Date: | April 2, 2021 | ||||
| ITEM | SPECIFICATION | RESULTS | ||||
| Description: Appearance Odor&Taste Particle size Extract Solvent |
Faint yellow fine Powder Characteristics 100% pass 80 mesh sieve Ethanol & Water |
Conforms Conforms Conforms Conforms |
||||
| Assay: Osthole |
≥90% by HPLC | 90.39% | ||||
| Physical: Loss on Drying Total Ash |
≤5.0 % ≤5.0 % |
0.52% 0.39% |
||||
| Chemical: Heavy Metals Arsenic (As) Lead (Pb) Mercury (Hg) Cadmium (Cd) |
≤10 ppm ≤2ppm ≤5ppm ≤0.1ppm ≤1ppm |
Conforms Conforms Conforms Conforms Conforms |
||||
| Microbial: Total Plate Count Yeast & Mold E. Coli Salmonella spp Staphylococcus aureus Pseudomonas aeruginosa |
≤1000cfu/g ≤100cfu/g Absent Absent Absent Absent |
Conforms Conforms Conforms Conforms Conforms Conforms |
||||
Conclusion: Conform to specification.
Storage: Store in cool & dry place. Keep away from strong light and heat.
Shelf life: 24 months when properly stored.
Chromatogram For Reference
