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Hypericum Perforatum Extract, St. John’s Wort Extract

Short Description:

  1. Synonyms:St. John’s Wort Extract, Hypericin, Pseudo-hypericin
  2. Appearance: Dark Brown Fine Powder
  3. Active ingredients:Naphthodianthrones (Hypericin, Pseudohypericin, Protohypericin, Protopseudohypericin etc.)

Product Detail

Product Tags

Specification

0.3% Hypericins by UV
0.45% Hypericins by UV
0.5% Hypericins by UV
0.6% Hypericins by UV
0.75% Hypericins by UV

0.1% Hypericin by HPLC
0.2% Hypericin by HPLC
0.3% Hypericin by HPLC
0.45% Hypericin by HPLC
0.75% Hypericin by HPLC

We also have double standardized product as 0.45% Hypericins by UV, 0.2% Hypericin by HPLC

Introduction

Hypericum perforatum L. Hypericum perforatum, known as perforate St John's-wort, common Saint John’s wort and St John’s wort, is a flowering plant in the family Hypericaceae. Hypericum perforatum is native to parts of Europe and Asia but has spread to temperate regions worldwide as a cosmopolitan invasive weed

The whole herbal St. John’s Wort (Hypericum perforatum L.) contains:
1) naphthodianthrones: which are Hypericin, Pseudohypericin, Protohypericin, Protopseudohypericin, Cyclopseudohypericin, Isohypericin, Emodin-anthrone, Hypericode-hydrodianthrone etc.
2)Flavonoids: including Kampferol Luteolin, Myricetin, Quercetin, Quercitrin, Isoquercitrin, 3)Hyperin/Hyperoside etc. Hyperforin substance: Hyperforin Adhyperforin etc.

The St. John's Wort Extract (also called as Hypericum Perforatum Extract) powder (Hypericins) is extracted from tips and tops in flowering or aerial parts, all our extracted are extracted by ethanol (food grade). Our material comes from a special producing area, which can guarantee the high quality to produce higher content of Hypericin.

Hypericin (Molecular Formula: C30H16O8, Molecular Weight: 504.43
CAS NO. 548-04-9)
is a naphthodianthrone, an anthraquinone derivative which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort) Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.

Application

1) Anti-depression effect
The hypericin, an active ingredient from the St. John’s Wort extract has Anti-depressive and sedative properties, it is an effective remedy for the nervous system, relaxing tension, and anxiety and lifting the spirits, Enhancing the effect of neurotransmitters in the brain, As a tissue restorative for nerves, St. John’s Wort is indicated for stroke patients, for mild neuroses, sleepwalkers, and accident victims. So it is usually used in tablet, capsule or oral liquid as medicine and also as an additive in functional or healthy food.

2) Anti-viral disease

The two ingredients Hypericin and Pseudohypericin directly act on viral disease.

3) Anti -Cancer

4) Anti-inflammatory
The bis-flavonoid in the St. John’s Wort can activate the hemameba to affect Anti-inflammatory.

5) Antibacterial
The Hyperforin substance has the property of Antibacterial to inhabit the growing of Staphylococcus aureus, Corynebacterium diphtheria, Antistaphylococcal Penicillins.

6) An excellent feed additive
The St. John’s Wort powder has a very good prevention and treatment for avian influenza, Swine fever, foot-and-mouth disease, and a strong Inhibition of Viral Replication by RNA Interference in Animals.

Certificate of Analysis For Reference

Product Name: St. John’s Wort Extract Latin Name: Hypericum perforatum L.
Batch Number: 20210323 Used Part: Herb with Flowers
Batch Quantity: 1500KG Analysis Date: March 23, 2021
Manufacture Date: March 23, 2021 Certificate Date: March 30, 2021

ITEM

SPECIFICATION

RESULTS

Description:Appearance
Odor
Particle size
Extract Solvents
Deep Brown Powder
Characteristic
95% pass 80 mesh sieve
Ethanol and Water

Conforms

Conforms

Conforms

Conforms

Assay:Hypericins by UV≥0.3%

0.302%

Physical:Loss on Drying
Total Ash
Bulk Density
≤5%
≤10%
40-60g/100ml

2.37%

8.94%

58g/100ml

Chemical:Arsenic (As)
Lead (Pb)
Cadmium (Cd)
Mercury (Hg)
Heavy Metals
≤2ppm
≤5ppm
≤1ppm
≤0.1ppm
≤10ppm

0.150ppm

0.068ppm

0.078ppm

0.013ppm

Conforms

Microbial:Total Plate Count
Yeast & Mold
E.Coli
Salmonella
≤1000cfu/g Max
≤100cfu/g Max
Negative
Negative

10cfu/g

10cfu/g

Conforms

Conforms

Conclusion Conform to specification.
Storage Store in cool & dry place. Keep away from strong light and heat.
Shelf life Two years when properly stored.

Chromatogram For Reference

Hypericin standard HPLC

Hypericum Perforatum Extract
Hypericum Perforatum Extract
Hypericum Perforatum Extract

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