Milk Thistle Extract, Silymarin, Silybin
Specification
70%-80% Silymarin
80%Silymarin, 45%HPLC (30% Silybin&Isosilybin) extracted by Actone USP
50% Silymarin + 30% Silybin extracted by Actone USP
60% Silymarin + 40% Silybin extracted by Actone
80%Silymarin, 45%HPLC (30% Silybin&Isosilybin) extracted by Ethyl Acetate USP
50% Silymarin + 30% Silybin extracted by Ethyl Acetate USP
55% Silymarin + 35% Silybin extracted by Ethyl Acetate
80%Silymarin, 45%HPLC (30% Silybin&Isosilybin) extracted by Ethanol USP
50% Silymarin + 30% Silybin extracted by Ethanol USP
55% Silymarin + 35% Silybin extracted by Ethanol
Water soluble 20%-40% Silymarin
80%-99% Silybin
Introduction
Milk Thistle, (also called as Silybum marianum(L.) Gaertn. or Carduus marianus L.), its seed contains a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others, Silibinin itself is a mixture of two diastereomers, silybin A and silybin B in approximately equimolar ratio. The mixture exhibits a number of pharmacological effects, particularly in the fatty liver, non-alcoholic fatty liver, non-alcoholic steatohepatitis, the silymarin has the antioxidant, antiviral and anti-inflammatory properties
Milk Thistle Extract is extracted from the seed of the plant "Silybum marianum(L.) Gaertn. or Carduus marianus L." through different solvents as Actone, Ethyl Acetate and Ethanol.
Silybin (Silibinin, Silybinin, CAS NO.22888-70-6, Mocular:C25H22O10) a natural polyphenolic flavonoid, is a major bioactive component of silymarin isolated from the plant milk thistle (Silybum marianum) that has been extensively used in treating hepatic ailments in Asia and Europe.
Application
1) Liver Protecting
The silymarin have reproductive function of hepatocytes to stimulate the new cells form; and also produce protective film on hepatocytes to precaution of viral penetration to hepatocytes. It is used in medicine of live protection, such as tablet, capsule.
2) Excellent Antioxidant
It can clear free radical in human body, postpone senility.
3) Preventing Arteriosclerosi
4) A natural feed additive against hepatotoxic effects of feed aflatoxins
Function of silymarin in Feed protects against hepatotoxic effects of feed aflatoxins, Mycotoxins not only reduce animal performance, but they also cause significant liver damage. The seeds of the herb plant milk thistle contain a mixture of flavonolignans known as silymarin and can help in reducing liver damage when animals get in contact with mycotoxin contaminated feed.
Certificate Of Analysis For Reference
Product Name: | Milk thistle Extract | Latin Name: | Silybum marianum (L.)Gaertn | |
Batch Number: | 20200927 | Used Part: | Seed | |
Batch Quantity: | 1000KG | Analysis Date: | Sept. 27, 2020 | |
Manufacture Date: | Sept. 27, 2020 | Certificate Date: | Sept. 30, 2020 |
ITEM | SPECIFICATION | RESULTS |
Description: Appearance Odor Particle size Extract Solvents |
Yellowish Brown Powder Characteristic 100% pass 80 mesh sieve Acetone and Hexane |
Conforms Conforms Conforms Conforms |
Assay: Silymarin Silymarin calculated as Silybin (dry) Silybins & Isosilybins |
≥80% by UV by HPLC ≥30% by HPLC |
82.24% 49.54% 36.32% |
Physical: Loss on Drying Sulphated Ash |
≤5% ≤0.6% |
2.83% 0.21% |
Chemical: Arsenic (As) Lead (Pb) Mercury (Hg) Cadmium (Cd) Heavy Metals Solvent Residue Hexane Acetone |
≤2ppm ≤5ppm ≤0.1ppm ≤1ppm ≤20ppm ≤290ppm ≤5000ppm |
Conforms Conforms Conforms Conforms Conforms Conforms 12ppm 3800ppm |
Microbial: Total Plate Count Yeast & Mold E.Coli Salmonella Staphylococcus Aflatoxins |
≤1000cfu/g Max ≤100cfu/g Max Negative Negative Negative ≤20ppm |
<10cfu/g <10cfu/g Conforms Conforms Conforms Non Detective |
Conclusion: Conform to specification of EP 6.0 and CP
Storage: Store in cool & dry place. Keep away from strong light and heat.
Shelf life: 2 years when properly stored.