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White Willow Bark Extract Salicin

Short Description:

  • Synonyms: Salix Alba Bark Extract, White Willow Extract, Salix Extract
  • Appearance: Brown to White Fine Powder
  • Active ingredients: Phenolic glycoside (Salicin, Salicortin, Tremulacin, Fragilin etc), flavonoids glycoside (Isorhamnetin, Quercitrin etc.)

Product Detail

Product Tags

Specification

15% Salicin by HPLC
25% Salicin by HPLC
50% Salicin by HPLC
98% Salicin by HPLC

Introduction

White willow bark extract (as called as Salix Alba Bark Extract, Salix Extract) is a product extracted from the dried bark or dried twig of White willow, the plant name “Salix alba L.” The Main active ingredients in White willow bark extract (also called Cortex Salicis Extract) are phenolic glycosides and flavones glycosides.

Salicin (CAS NO. 138-52-3, C13H18O7) is an alcoholic β-glucoside. Salicin is produced in (and named after) willow (Salix) bark. It is a biosynthetic precursor to salicylaldehyde.

Salicin acts as an anti-inflammatory agent. Salicin is also commonly found in the bark of Populus species, and the leaves of willows and poplars, which was used as an analgesic, anti-inflammatory, and antipyretic. Salicin is transformed to salicylic acid and has an action very similar to that of aspirin. Salicin was the historical origin of aspirin and is chemically related to it. When consumed, the acetalic ether bridge is broken down. The two parts of the molecule, glucose and salicyl alcohol, then are metabolized separately. By oxidizing the alcohol functional group, the aromatic part finally is metabolized to salicylic acid. Salicin tastes bitter like quinine.

Application

1) A natural ingredient of antimicrobial bactericidal bioactivity.

The White willow Bark Extract ( Cortex salicis extract) is rich in phenolic glycosides and flavones glycosides, which has strong inhibition on Aspergillus niger, Bacillus subtilis, candida albicans, Escherichia coli, Pseudomonas aeruginosa etc. Also has autoxidation activity. So the white willow bark extract is usually used to produce natural food preservatives; in cosmetics, it can Prevent acne, reduce swelling and pain, so it protects skin, Anti – dandruff.

2) The Salicin as a natural “Aspirin”

The Salicin can be converted into salicylic acid; it can treat fever, cold and infection in the field of medicine.

3) The Salicin as a natural feed additive of anti-inflammatory and helping digestion for animal.

 

Certificate of Analysis For Reference

Product Name: Salix Alba White Willow Extract Latin Name: Salix Alba L
Batch Number: 20210110 Used Part: Branch and Bark
Batch Quantity: 2600KG Analysis Date: Dec. 17, 2020
Manufacture Date: Dec. 17, 2020 Certificate Date: Jan. 27, 2021

ITEM

SPECIFICATION

RESULTS

Description:
Appearance
Odor
Particle size
Extract Solvents
Brown Yellow to Off White fine Powder
Characteristic
100% pass 80 mesh sieve
Methanol and Water

Light Yellow Color
Conforms
Conforms
Conforms

Assay:
Salicin
by HPLC
≥50%

50.62%

Physical:
Solubility
Loss on Drying
Total Ash
Bulk Density
Good solubility in water
≤5%
≤20%
45-60g/100ml

Conforms
2.00%
7.40%
56g/100ml

Chemical:
Arsenic (As)
Lead (Pb)
Cadmium (Cd)
Mercury (Hg)
Heavy Metals
Solvent Residue
≤2ppm
≤5ppm
≤1ppm
≤0.1ppm
≤10ppm
≤100ppm

Conforms
Conforms
Conforms
Conforms
Conforms
20ppm

Microbial:
Total Plate Count
Yeast & Mold
E.Coli
Salmonella
Staphylococcus
≤1000cfu/g Max
≤100cfu/g Max
Negative
Negative
Negative

Conforms
Conforms
Conforms
Conforms
Conforms

Conclusion: Conform to specification.
Storage: Store in cool & dry place. Keep away from strong light and heat.
Shelf life: 12 month when properly stored.

Chromatogram For Reference

White Willow Bark Extract Salicin

 

white willow bark extract01
white willow bark extract02
white willow bark extract03
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