White Willow Bark Extract Salicin
Specification
15% Salicin by HPLC
25% Salicin by HPLC
50% Salicin by HPLC
98% Salicin by HPLC
Introduction
White willow bark extract (as called as Salix Alba Bark Extract, Salix Extract) is a product extracted from the dried bark or dried twig of White willow, the plant name “Salix alba L.” The Main active ingredients in White willow bark extract (also called Cortex Salicis Extract) are phenolic glycosides and flavones glycosides.
Salicin (CAS NO. 138-52-3, C13H18O7) is an alcoholic β-glucoside. Salicin is produced in (and named after) willow (Salix) bark. It is a biosynthetic precursor to salicylaldehyde.
Salicin acts as an anti-inflammatory agent. Salicin is also commonly found in the bark of Populus species, and the leaves of willows and poplars, which was used as an analgesic, anti-inflammatory, and antipyretic. Salicin is transformed to salicylic acid and has an action very similar to that of aspirin. Salicin was the historical origin of aspirin and is chemically related to it. When consumed, the acetalic ether bridge is broken down. The two parts of the molecule, glucose and salicyl alcohol, then are metabolized separately. By oxidizing the alcohol functional group, the aromatic part finally is metabolized to salicylic acid. Salicin tastes bitter like quinine.
Application
1) A natural ingredient of antimicrobial bactericidal bioactivity.
The White willow Bark Extract ( Cortex salicis extract) is rich in phenolic glycosides and flavones glycosides, which has strong inhibition on Aspergillus niger, Bacillus subtilis, candida albicans， Escherichia coli， Pseudomonas aeruginosa etc. Also has autoxidation activity. So the white willow bark extract is usually used to produce natural food preservatives; in cosmetics, it can Prevent acne, reduce swelling and pain, so it protects skin, Anti – dandruff.
2) The Salicin as a natural “Aspirin”
The Salicin can be converted into salicylic acid; it can treat fever, cold and infection in the field of medicine.
3) The Salicin as a natural feed additive of anti-inflammatory and helping digestion for animal.
Certificate of Analysis For Reference
| Product Name: | Salix Alba White Willow Extract | Latin Name: | Salix Alba L |
| Batch Number: | 20210110 | Used Part: | Branch and Bark |
| Batch Quantity: | 2600KG | Analysis Date: | Dec. 17, 2020 |
| Manufacture Date: | Dec. 17, 2020 | Certificate Date: | Jan. 27, 2021 |
|
ITEM |
SPECIFICATION |
RESULTS |
| Description: Appearance Odor Particle size Extract Solvents |
Brown Yellow to Off White fine Powder Characteristic 100% pass 80 mesh sieve Methanol and Water |
Light Yellow Color |
| Assay: Salicin |
by HPLC ≥50% |
50.62% |
| Physical: Solubility Loss on Drying Total Ash Bulk Density |
Good solubility in water ≤5% ≤20% 45-60g/100ml |
Conforms |
| Chemical: Arsenic (As) Lead (Pb) Cadmium (Cd) Mercury (Hg) Heavy Metals Solvent Residue |
≤2ppm ≤5ppm ≤1ppm ≤0.1ppm ≤10ppm ≤100ppm |
Conforms |
| Microbial: Total Plate Count Yeast & Mold E.Coli Salmonella Staphylococcus |
≤1000cfu/g Max ≤100cfu/g Max Negative Negative Negative |
Conforms |
Conclusion: Conform to specification.
Storage: Store in cool & dry place. Keep away from strong light and heat.
Shelf life: 12 month when properly stored.
Chromatogram For Reference
